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Scleritis can be classified as anterior scleritis and posterior scleritis. Anterior scleritis is the most common variety, accounting for about 98% of the cases. It is of two types : Non-necrotising and necrotising. Non-necrotising scleritis is the most common, and is further classified into diffuse and nodular type based on morphology.
If there is an underlying cause, treatment should be given based on the disease. Non specific treatment measures include cycloplegics , corticosteroids and immunosuppressive drugs . [ 2 ] The biologic drugs that are currently used in treatment of panuveitis include anti tumor necrosis factor , cytokine receptor antibodies and interferon-α .
Uveitis is described anatomically, by the part of the eye affected, as anterior, intermediate or posterior, or panuveitic if all parts are involved. Anterior uveitis ( iridocyclitis ) is the most common, with the incidence of uveitis overall affecting approximately 1:4500, most commonly those between the ages of 20–60.
Episcleritis is a benign, self-limiting condition, meaning patients recover without any treatment. Most cases of episcleritis resolve within 7–10 days. [2] The nodular type is more aggressive and takes longer to resolve. [2] Although rare, some cases may progress to scleritis. [13]
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[3] [6] [4] [8] [9] The most common forms of ocular involvement are usually mild and often consist of unilateral or bilateral episcleritis and/or scleritis, that is often anterior and could be lingering or relapsing. [3] [4] Scleritis that is necrotizing is found to be exceedingly rare. [3] Less often, conjunctivitis occurs.
Scleritis is a serious inflammatory disease of the sclera causing redness of the sclera often progressing to purple. Yellowing or a light green color of the sclera is a visual symptom of jaundice. In cases of osteogenesis imperfecta, the sclera may appear to have a blue tint, more pronounced than the slight blue tint seen in children.
The condition of posterior staphyloma in high myopia was first described by Scarpa in the 1800s. [6] Speculation about reinforcement of the eye began in the 19th century, when Rubin noted that sclera reinforcement “is probably the only one of all the surgical techniques [for myopia] which attempts to correct a cause, rather than an effect”. [7]
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