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Common side effects include loss of appetite, gastrointestinal upset, constipation, and low blood calcium. [1] These polymers are derived from polystyrene by the addition of sulfonate functional groups. Sodium polystyrene sulfonate was approved for medical use in the United States in 1958. [1]
Hypokalemia, hypomagnesaemia, nausea or vomiting are side effects commonly seen when polystyrene resins are used. Cases of colonic necrosis have been reported, particularly when sodium polystyrene sulfonate was used in combination with the laxative sorbitol. Additionally, electrolyte disturbances, systemic alkalosis or gastric irritation may occur.
These methods include polystyrene microspheres, nanoparticles, and solid foams. In the biomedical engineering field, these methods assist researchers in drug delivery, diagnostics, and imaging strategies. [1] [2] A common group of medication that utilizes a combination of polystyrene and sulfonate functional groups are polystyrene sulfonates. [3]
Tolevamer was designed to bind the enterotoxins of Clostridioides difficile.Since it has no antibiotic properties, it does not harm the gut flora.Early studies used the sodium salt, but it was soon replaced with the potassium sodium salt to prevent hypokalaemia, which is often associated with diarrhea.
The structure of sodium polystyrene sulfonate is shown. When this salt is dissolved in a solvent, the negatively charged side group can adsorb positively charged adsorbates. When this salt is dissolved in a solvent, the negatively charged side group can adsorb positively charged adsorbates.
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related to: effectiveness of sodium polystyrene sulfonate- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
"The lowest prices on specific drugs" - Family Circle