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Nevi and melanomas are a group of neoplasia. Although a nevus and a melanoma are often treated as independent entities, there is evidence that a nevus can be a precursor for a melanoma. [1] Common mutations have been identified in nevi and melanomas. [2] [3] [4]
A nevus is a benign, freckle in the eye. These should be checked out and regular checks on the eye done to ensure it has not turned into a melanoma. Iris and conjuctival tumors (melanomas) - Present as a dark spot. Any spot which continues to grow on the iris and the conjunctiva should be checked out.
Choroidal nevus (plural: nevi) is a type of eye neoplasm that is classified under choroidal tumors as a type of benign (non-cancerous) melanocytic tumor. [1] A choroidal nevus can be described as an unambiguous pigmented blue or green-gray choroidal lesion, found at the front of the eye, around the iris, [2] or the rear end of the eye.
Some melanocytic nevi, and melanoma-in-situ (lentigo maligna) have resolved with an experimental treatment, imiquimod (Aldara) topical cream, an immune enhancing agent. Some derma-surgeons are combining the two methods: surgically excising the cancer and then treating the area with Aldara cream postoperatively for three months.
Uveal melanoma is a type of eye cancer in the uvea of the eye. [3] It is traditionally classed as originating in the iris, choroid, and ciliary body, but can also be divided into class I (low metastatic risk) and class II (high metastatic risk). [3]
The features include: 1) two or more clinically atypical nevi, 2) more than 100 nevi in patients between 20 and 50 years of age, 3) more than 50 nevi in patients under 20 years of age or more than 50 years of age, 4) more than one nevus in buttocks or instep, 5) nevi on the anterior scalp, 6) one or more pigmented lesions in the iris.
M8720/0 Pigmented nevus, NOS Melanocytic nevus; Nevus, NOS; Hairy nevus; M8720/2 Melanoma in situ M8720/3 Malignant melanoma, NOS (except juvenile melanoma M8770/0) Melanoma, NOS; M8721/3 Nodular melanoma. M8722/0 Balloon cell nevus M8722/3 Balloon cell melanoma M8723/0 Halo nevus Regressing nevus; M8723/3 Malignant melanoma, regressing M8725/0 ...
Ocular melanosis (OM) is a blue-gray and/or brown lesion of the conjunctiva that can be separated into benign conjunctival epithelial melanosis (BCEM) and primary acquired melanosis (PAM), of which the latter is considered a risk factor for uveal melanoma. [1]
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