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Ophthalmodynia periodica does not have a confirmed cause, being a primary headache, but can be identified with other primary conditions. "As many as 40% of all individuals with ice pick headaches have also been diagnosed as suffering with some form of migraine headache." [4]
The symptoms of fungal keratitis typically emerge over 5-10 days and present with a painful eye, blurred vision, and redness of eye. [1] There is increased sensitivity to light, and excessive tears or discharge. [1] The symptoms are markedly less as compared to a similar bacterial ulcer. [1]
Chronic paroxysmal hemicrania (CPH) is a severe debilitating unilateral headache usually affecting the area around the eye. It normally consists of multiple severe, yet short, headache attacks affecting only one side of the cranium. Retrospective surveys indicated that paroxysmal hemicrania was more common in women.
Around 6% of infants have congenital nasolacrimal duct obstruction, or dacryostenosis, usually experiencing a persistent watery eye even when not crying. If a secondary infection occurs (dacryocystitis), purulent (yellow / green) discharge may be present. Most cases resolve spontaneously, with antibiotics reserved only if conjunctivitis occurs.
Treatment includes a healthy diet, salt restriction, and exercise. [2] The medication acetazolamide may also be used along with the above measures. [2] A small percentage of people may require surgery to relieve the pressure. [2] About 2 per 100,000 people are newly affected per year. [4] The condition most commonly affects women aged 20–50. [2]
Side effects include burning sensation (common), [4] redness, discharge, watery eyes, eye pain, foreign body sensation, itching, stinging, and blurred vision. [14] [4] Long term use of ciclosporin at high doses is associated with an increased risk of cancer. [48] [49] Cheaper generic alternatives are available in some countries. [50]
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A clinician may often depend upon patient history and exam to diagnose, for example: discharge of excessive amount of clear fluid from the nose upon bending over, the increase in headache following a Valsalva maneuver or the reduction of headache when the patient takes a prone position are positive indicators.