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The senator Robert Byrd, after winning re-election in 2000, is quoted as saying, "West Virginia has always had four friends, God Almighty, Sears Roebuck, Carter's Liver Pills and Robert C. Byrd." [6] A Carter's Little Liver Pills ad was featured in Joe Dante's 1968 collage parody film The Movie Orgy. [7]
The Indonesian Food and Drug Authority (Indonesian: Badan Pengawas Obat dan Makanan, lit. 'Food and Drug Supervisory Agency'), Badan POM/BPOM, or Indonesian FDA is a government agency of Indonesia responsible for protecting public health through the control and supervision of prescription and over-the-counter pharmaceutical drugs (medication), vaccines, biopharmaceuticals, dietary supplements ...
Since this mostly happens in the liver, this is the most affected organ. Other affected organs are the lungs and kidneys. The EPy can escape the liver, and travel through the Disse space into the bloodstream. The electrophilic nature of pyrroles makes it an easy target for nucleophilic attack from nucleic acids and protein.
Indonesia is the only country that makes single-component dextromethorphan illegal over the counter and by prescription [51] and violators may be prosecuted by law. National Anti-Narcotics Agency (BNN RI) has threatened to revoke pharmacies' and drug stores' licenses if they still stock dextromethorphan, and will notify the police for criminal ...
Rarely, people with the hepatitis A virus can rapidly develop liver failure, termed fulminant hepatic failure, especially the elderly and those who had a pre-existing liver disease, especially hepatitis C. [17] [80] Mortality risk factors include greater age and chronic hepatitis C. [17] In these cases, more aggressive supportive therapy and ...
Acetylcysteine is extensively liver metabolized, CYP450 minimal, urine excretion is 22–30% with a half-life of 5.6 hours in adults and 11 hours in newborns. [ medical citation needed ] Acetylcysteine is the N - acetyl derivative of the amino acid L -cysteine, and is a precursor in the formation of the antioxidant glutathione in the body.
A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. [1] [2] Instead of administering a drug directly, a corresponding prodrug can be used to improve how the drug is absorbed, distributed, metabolized, and excreted ().
Liver regeneration is the process by which the liver is able to replace damaged or lost liver tissue. The liver is the only visceral organ with the capacity to regenerate. [ 1 ] [ 2 ] The liver can regenerate after partial hepatectomy or injury due to hepatotoxic agents such as certain medications, toxins, or chemicals. [ 3 ]