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STR analysis is a tool in forensic analysis that evaluates specific STR regions found on nuclear DNA. The variable (polymorphic) nature of the STR regions that are analyzed for forensic testing intensifies the discrimination between one DNA profile and another. [3] Scientific tools such as FBI approved STRmix incorporate this research technique.
In computer programming, profile-guided optimization (PGO, sometimes pronounced as pogo [1]), also known as profile-directed feedback (PDF) [2] or feedback-directed optimization (FDO), [3] is the compiler optimization technique of using prior analyses of software artifacts or behaviors ("profiling") to improve the expected runtime performance of the program.
Python: Python profiling includes the profile module, hotshot (which is call-graph based), and using the 'sys.setprofile' function to trap events like c_{call,return,exception}, python_{call,return,exception}. Ruby: Ruby also uses a similar interface to Python for profiling. Flat-profiler in profile.rb, module, and ruby-prof a C-extension are ...
From country to country, different STR-based DNA-profiling systems are in use. In North America, systems that amplify the CODIS 20 [21] core loci are almost universal, whereas in the United Kingdom the DNA-17 loci system is in use, and Australia uses 18 core markers. [22] The true power of STR analysis is in
In information science, profiling refers to the process of construction and application of user profiles generated by computerized data analysis. This is the use of algorithms or other mathematical techniques that allow the discovery of patterns or correlations in large quantities of data, aggregated in databases .
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Strand 1 differs from strand 2 at a single base pair location (a C → T polymorphism). A person's haplogroup can often be inferred from their STR results, but can be proven only with a Y-chromosome SNP test (Y-SNP test). A single-nucleotide polymorphism (SNP) is a change to a single nucleotide in a DNA sequence.
The basis for the profile probability estimation for Y-STR analysis is the counting method. [4] The application of a confidence interval accounts for database size and sampling variation. The Y haplotype frequency (p) is calculated using the p = x/N formula, where x is equal to the number of times the haplotype is observed in a database ...