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  2. Cholesterol - Wikipedia

    en.wikipedia.org/wiki/Cholesterol

    Cholesterol is the principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. [3] [4]Cholesterol is biosynthesized by all animal cells [citation needed] and is an essential structural and signaling component of animal cell membranes.

  3. Lipid metabolism - Wikipedia

    en.wikipedia.org/wiki/Lipid_metabolism

    Lipid metabolism is the synthesis and degradation of lipids in cells, involving the breakdown and storage of fats for energy and the synthesis of structural and functional lipids, such as those involved in the construction of cell membranes. In animals, these fats are obtained from food and are synthesized by the liver. [1]

  4. Cholesterol total synthesis - Wikipedia

    en.wikipedia.org/wiki/Cholesterol_total_synthesis

    Cholesterol total synthesis in chemistry describes the total synthesis of the complex biomolecule cholesterol and is considered a great scientific achievement. [1] The research group of Robert Robinson with John Cornforth ( Oxford University ) published their synthesis in 1951 [ 2 ] and that of Robert Burns Woodward with Franz Sondheimer ...

  5. Low-density lipoprotein - Wikipedia

    en.wikipedia.org/wiki/Low-density_lipoprotein

    where H is HDL cholesterol, L is LDL cholesterol, C is total cholesterol, T are triglycerides, and k is 0.20 if the quantities are measured in mg/dL and 0.45 if in mmol/L. There are limitations to this method, most notably that samples must be obtained after a 12 to 14 h fast and that LDL-C cannot be calculated if plasma triglyceride is >4.52 ...

  6. HMG-CoA reductase - Wikipedia

    en.wikipedia.org/wiki/HMG-CoA_reductase

    HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, official symbol HMGCR) is the rate-controlling enzyme (NADH-dependent, EC 1.1.1.88; NADPH-dependent, EC 1.1.1.34) of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids.

  7. 7-Dehydrocholesterol - Wikipedia

    en.wikipedia.org/wiki/7-Dehydrocholesterol

    This is the next-to-last step of cholesterol biosynthesis. [4] Defective synthesis results in the human inherited disorder lathosterolosis resembling Smith–Lemli–Opitz syndrome. [4] Mice where this gene has been deleted lose the ability to increase vitamin D 3 in the blood following UV exposure of the skin. [5]

  8. We all need HGH, the hormone responsible for growth. What ...

    www.aol.com/hgh-hormone-responsible-growth...

    In children, HGH stimulates linear growth and protein synthesis. It also helps with the breakdown of lipids fat, says O’Sullivan. In adults, HGH helps regulate blood glucose levels, she adds.

  9. Lanosterol synthase - Wikipedia

    en.wikipedia.org/wiki/Lanosterol_synthase

    Figure 1: Lanosterol synthase mechanism. The discrete carbocation intermediates show the non-concerted nature of the mechanism. Though some data on the mechanism has been obtained by the use of suicide inhibitors, mutagenesis studies, and homology modeling, it is still not fully understood how the enzyme catalyzes the formation of lanosterol.

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