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GM2A is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T-cell activation through lipid presentation. This protein binds molecules of ganglioside GM2, extracts them from membranes, and presents them to beta- hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
A transcriptional activator is a protein (transcription factor) that increases transcription of a gene or set of genes. [1] Activators are considered to have positive control over gene expression, as they function to promote gene transcription and, in some cases, are required for the transcription of genes to occur.
Activator (Ac)/ Dissociation (Ds) transposable elements were discovered by Barbara McClintock when she was studying the maize genomic composition of the short arm of chromosome 9. She noticed that when chromosome 9 had been exposed to drastic structural modifications, the progeny had changes such as multiple copies of the short arm or lacking ...
29851 54167 Ensembl ENSG00000163600 ENSMUSG00000026009 UniProt Q9Y6W8 Q9WVS0 RefSeq (mRNA) NM_012092 NM_017480 RefSeq (protein) NP_036224 NP_059508 Location (UCSC) Chr 2: 203.94 – 203.96 Mb Chr 1: 61.02 – 61.04 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Inducible T-cell costimulator (also called CD278) is an immune checkpoint protein that in humans is encoded by the ICOS (I ...
Paula Abdul and Nigel Lythgoe have reached a settlement in their lawsuit.. According to court documents obtained by PEOPLE, the pair settled the case, in which Abdul accused the producer of sexual ...
In all cases, CAK tends to be in constant excess in the cell, so that cyclin binding is the rate-limiting step in Cdk activation. CDK-activating kinase (CAK) activates the cyclin- CDK complex by phosphorylating threonine residue 160 in the CDK activation loop .
Cher is opening up about losing her virginity as a teenager.. In her new memoir Cher: The Memoir, Part One, which was released on Tuesday, Nov. 19, the singer and actress recalls the circumstances ...
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