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The term high-functioning autism was used in a manner similar to Asperger syndrome, another outdated classification. The defining characteristic recognized by psychologists was a significant delay in the development of early speech and language skills, before the age of three years. [ 12 ]
A 2003 review of epidemiological studies of children found autism rates ranging from 0.03 to 4.84 per 1,000, with the ratio of autism to Asperger syndrome ranging from 1.5:1 to 16:1; [142] combining the geometric mean ratio of 5:1 with a conservative prevalence estimate for autism of 1.3 per 1,000 suggests indirectly that the prevalence of AS ...
In 2013, one study reported that 60% and 44% of 93 children with ASD were positive for FRα-blocking and binding autoantibodies, respectively. This high rate of anti-FRα autoantibody positivity was confirmed by Ramaekers et al. who compared 75 children with ASD to 30 non-autistic "controls".
Autistic children are less likely to make requests or share experiences and more likely to simply repeat others' words . [105] The CDC estimated in 2015 that around 40% of autistic children do not speak at all. [106] Autistic adults' verbal communication skills largely depend on when and how well speech is acquired during childhood. [102]
The Childhood Autism Rating Scale (CARS) is a behavior rating scale intended to help diagnose autism. CARS was developed by Eric Schopler , Robert J. Reichler , and Barbara Rochen Renner . The scale was designed to help differentiate children with autism from those with other developmental delays, such as intellectual disability .
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Classic autism, also known as childhood autism, autistic disorder, or Kanner's syndrome, is a formerly diagnosed neurodevelopmental disorder first described by Leo Kanner in 1943. It is characterized by atypical and impaired development in social interaction and communication as well as restricted, repetitive behaviors, activities, and interests.
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