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The accumulation of red blood cells in the spleen results in a sudden drop in circulating hemoglobin and potentially life-threatening anemia. Symptoms include pain on the left side, swollen spleen (which can be detected by palpation), fatigue, dizziness, irritability, rapid heartbeat, or pale skin. It most commonly affects young children, the ...
Drop in hemoglobin level, fever, jaundice, or hemoglobinuria, as well as chills, abdominal pain, or back pain: Usual onset: Generally up to one month: Causes: Transfusion of mismatched blood types, reactivity of recipient's antibodies against donor's red blood cell proteins, or prior damage to red blood cells contained in transfusion products ...
A hemoglobin test measures the amount of hemoglobin in your blood. If a hemoglobin tests shows that a person's levels are below normal, it means they have a low red blood cell count, which is known as anemia. If the test shows higher levels than normal, it means they have hemoglobinemia. [citation needed] The normal range for hemoglobin is:
Drug-induced autoimmune hemolytic anemia causes a significant drop in hemoglobin and hematocrit. Occasionally DIIHA can present with mild leukocytosis. In its earlier stages patients with DIIHA will have low reticulocytes. As HIIHA progresses reticulocytes increase leading to an elevated mean corpuscular volume.
Up to 30% of these children may develop splenic sequestration crisis with a mortality rate of up to 15%. This crisis occurs when splenic vaso-occlusion causes a large percentage of total blood volume to become trapped within the spleen. Clinical signs include severe, rapid drop in hemoglobin leading to hypovolemic shock and death.
Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen.This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin available for oxygen transport, or abnormalities in hemoglobin that impair its function.
[2] [3] However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency. [citation needed] Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes.
Most patients do not require medical intervention. Nevertheless, the rare chances of life-threatening acute drop in hemoglobin are always there and in which are deemed to develop hypovolemic shock and cardiac failure due to severe anemia, and to be complicated by acute tubular necrosis as a result of hemoglobinuria over the aftermath. [32]
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