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UNAIDS has said that HIV/AIDS in Indonesia is one of Asia's fastest growing epidemics. [1] In 2010, it is expected that 5 million Indonesians will have HIV/AIDS. [2] In 2007, Indonesia was ranked 99th in the world by prevalence rate, but because of low understanding of the symptoms of the disease and high social stigma attached to it, only 5-10% of HIV/AIDS sufferers actually get diagnosed and ...
The activation and proliferation of T cells that results from immune activation provides fresh targets for HIV infection. However, direct killing by HIV alone cannot account for the observed depletion of CD4 + T cells since only 0.01–0.10% of CD4 + T cells in the blood are infected. [citation needed]
At the household level, AIDS causes both loss of income and increased spending on healthcare. A study in Côte d'Ivoire showed that households having a person with HIV/AIDS spent twice as much on medical expenses as other households. This additional expenditure also leaves less income to spend on education and other personal or family investment.
The management of HIV/AIDS typically involves the use of multiple antiretroviral drugs. In many parts of the world, HIV has become a chronic condition, with progression to AIDS increasingly rare. HIV latency and the resulting viral reservoir in CD4 + T cells, dendritic cells, and macrophages is the main barrier to eradication of the virus. [19 ...
The pathophysiology of HIV/AIDS involves, upon acquisition of the virus, that the virus replicates inside and kills T helper cells, which are required for almost all adaptive immune responses. There is an initial period of influenza-like illness , and then a latent, asymptomatic phase.
A small proportion of humans show partial or apparently complete innate resistance to HIV, the virus that causes AIDS. [1] The main mechanism is a mutation of the gene encoding CCR5, which acts as a co-receptor for HIV. It is estimated that the proportion of people with some form of resistance to HIV is under 10%. [2]
The Evidence That HIV Causes AIDS Archived 24 September 2009 at the Wayback Machine: from the National Institute of Allergy and Infectious Diseases; How HIV Causes AIDS: National Institutes of Health fact sheet. Koch's Postulates and the Etiology of AIDS: An Historical Perspective Archived 5 January 2017 at the Wayback Machine
UNICEF reports that 10,946 children were HIV-positive, and 9,400 were orphaned by AIDS as of 2005. [1] A number of factors contribute to Papua New Guinea's growing HIV epidemic. Papua New Guinea shares an island with Papua, Indonesia, which has the highest HIV prevalence in Indonesia (4 percent) and has close to a third of all Indonesia's HIV ...