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Oxamniquine, sold under the brand name Vansil among others, is a medication used to treat schistosomiasis due to Schistosoma mansoni. [1] Praziquantel, however, is often the preferred treatment. [2] It is given by mouth and used as a single dose. [2] Common side effects include sleepiness, headache, nausea, diarrhea, and reddish urine. [1]
A schistosomicide is a drug used to combat schistosomiasis. [1] ... Schistosomiasis vaccine; ... "Current chemotherapy arsenal for schistosomiasis mansoni ...
Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. [4] While it may be used during pregnancy, it is not recommended for use during breastfeeding. [4] Praziquantel is in the anthelmintic class of medications. [3] It works partly by affecting the function of the worm's sucker. [3]
Schistosomiasis is treatable by taking a single dose of the drug praziquantel by mouth annually. [66] Praziquantel eliminates the adult schistosomes but does not kill the eggs and immature worms. [19] Live eggs can be excreted by the infected individuals for weeks after treatment with praziquantel. [19]
Sm-p80-based vaccine formulation(s) have four effects: Reduction in adult worm numbers; Reduction in egg production (complete elimination of egg induced pathology both in baboons and mice); Protection against acute schistosomiasis; Therapeutic effect on adult worms. This vaccine is now ready for human clinical trials. [5] [6] [7] Another target ...
Arpraziquantel ((R)-praziquantel) is the eutomer (the biologically active enantiomer) of praziquantel, and is a medication which is currently under investigation for the treatment of schistosomiasis in young children since it has less side effects than the usual racemic mixture formulation of praziquantel.
New RSV vaccines are now available to help prevent serious infection in people over 60. Doctors explain the RSV vaccine and its side effects in older adults.
Praziquantel is the drug of choice for schistosomiasis, taeniasis, and most types of food-borne trematodiases. Oxamniquine is also widely used in mass deworming programmes. Pyrantel is commonly used for veterinary nematodiasis. [45] [46] Artemisinins and derivatives are proving to be candidates as drugs of choice for trematodiasis. [47]
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