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A schistosomicide is a drug used to combat schistosomiasis. [1] ... praziquantel [3] stibophen; See also ... "Current chemotherapy arsenal for schistosomiasis mansoni ...
[11] [12] Praziquantel is also effective against Echinococcus multilocularis. [11] Schistosomiasis caused by trematodes of the genus Schistosoma: [13] As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose. [14] Clonorchiasis brought on by the Chinese liver fluke ...
Sm-p80-based vaccine formulation(s) have four effects: Reduction in adult worm numbers; Reduction in egg production (complete elimination of egg induced pathology both in baboons and mice); Protection against acute schistosomiasis; Therapeutic effect on adult worms. This vaccine is now ready for human clinical trials. [5] [6] [7] Another target ...
Schistosomiasis is treatable by taking by mouth a single dose of the drug praziquantel annually. [66] Praziquantel only eliminates the adult schistosomes, but it is not effective in killing the eggs and immature worms. [19] Live eggs can be excreted by the infected individuals for weeks after treatment with praziquantel. [19]
Arpraziquantel ((R)-praziquantel) is the eutomer (the biologically active enantiomer) of praziquantel, and is a medication which is currently under investigation for the treatment of schistosomiasis in young children since it has less side effects than the usual racemic mixture formulation of praziquantel.
Oxamniquine, sold under the brand name Vansil among others, is a medication used to treat schistosomiasis due to Schistosoma mansoni. [1] Praziquantel, however, is often the preferred treatment. [2] It is given by mouth and used as a single dose. [2] Common side effects include sleepiness, headache, nausea, diarrhea, and reddish urine. [1]
It is found in Africa and the Middle East. It is the major agent of schistosomiasis, the most prevalent parasitic infection in humans. [1] It is the only blood fluke that infects the urinary tract, causing urinary schistosomiasis, and is a leading cause of bladder cancer (only next to tobacco smoking). [2] [3] The diseases are caused by the eggs.
Schistosoma japonicum is an important parasite and one of the major infectious agents of schistosomiasis.This parasite has a very wide host range, infecting at least 31 species of wild mammals, including nine carnivores, 16 rodents, one primate (human), two insectivores and three artiodactyls and therefore it can be considered a true zoonosis.
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