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The efficacy of arsenic trioxide has also been demonstrated in the treatment of multiple myeloma, in combination with ascorbic acid [56] and bortezomib. [ 57 ] Animal studies have shown that the drug also affects ovarian, [ 58 ] liver, stomach, [ 59 ] prostate, and breast cancers, [ 60 ] as well as gliomas [ 61 ] and pancreatic cancer (in ...
Long-term ingestion of arsenic trioxide either in drinking water or as a medical treatment can lead to skin cancer. Reproductive problems (high incidences of miscarriage, low birth weight, congenital deformations) have also been indicated in one study of women exposed to arsenic trioxide dust as employees or neighbours of a copper foundry.
Non-small cell lung cancer, oesophageal cancer, uterine cervical cancer, head and neck cancer and urothelial cancer: Nephrotoxicity, myelosuppression and nausea and vomiting (30-90%). Oxaliplatin: IV: Reacts with DNA, inducing apoptosis, non-cell cycle specific. Colorectal cancer, oesophageal cancer and gastric cancer
Arsenic trioxide (As 2 O 3) inhibits cell growth and induces apoptosis (programmed cell death) in certain types of cancer cells, [23] which are normally immortal and can multiply without limit. In combination with all-trans retinoic acid , it is FDA-approved as first-line treatment for promyelocytic leukemia .
This treatment method is commonly linked with blood cancers like multiple myeloma, Hodgkin's lymphoma, and non-Hodgkin's lymphoma. It is also used in solid tumors such as germ cell tumors and certain high risk or recurrent breast cancers. Multiple myeloma, a type of plasma cell cancer [3] is an indication for HDC. Typically it follows stem cell ...
In homeopathy, arsenicum album (Arsenic. alb. ) is a solution prepared by diluting aqueous arsenic trioxide generally until there is little amounts of Arsenic remaining in individual doses. It is used by homeopaths to treat a range of symptoms that include digestive disorders and, as an application of the Law of Similars , has been suggested by ...
In 2020, the Australian equivalent of the FDA approved a testosterone cream for treatment of low sexual desire in postmenopausal women. Javaid has seen the benefits clinically, particularly ...
In chemistry, an arsenite is a chemical compound containing an arsenic oxyanion where arsenic has oxidation state +3. Note that in fields that commonly deal with groundwater chemistry, arsenite is used generically to identify soluble As III anions. IUPAC have recommended that arsenite compounds are to be named as arsenate(III), for example ...