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  2. List of drugs known for off-label use - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_known_for...

    Prazosin (Minipress) for nightmares: prazosin is approved for the use of hypertension. A 2012 systematic review showed a small benefit for the treatment of PTSD-associated night terrors. Other non-FDA-approved uses for prazosin include the treatment of Raynaud's disease and poisoning due to scorpion venom.

  3. Prazosin - Wikipedia

    en.wikipedia.org/wiki/Prazosin

    Prazosin, sold under the brand name Minipress among others, is a medication used to treat high blood pressure, symptoms of an enlarged prostate, and nightmares related to post-traumatic stress disorder (PTSD). [6] It is an α 1 blocker. [6] It is a less preferred treatment of high blood pressure. [6] Other uses may include heart failure and ...

  4. Alpha blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha_blocker

    High doses of the α 1 blocker, prazosin, have been efficacious in treating patients with PTSD induced nightmares due to its ability to block the effects of norepinephrine. [27] Adverse effects of prazosin to treat PTSD nightmares include dizziness, first dose effect (a sudden loss of consciousness), weakness, nausea, and fatigue. [27]

  5. Colorado school bus driver dismissed after 40 kids left at ...

    www.aol.com/colorado-school-bus-driver-dismissed...

    The driver ultimately drove to near the corner of East Wolfensberger Road and Auburn Drive, about 2 miles from the school, and he allegedly told the kids to disembark into the cold around 5 p.m.

  6. First-dose phenomenon - Wikipedia

    en.wikipedia.org/wiki/First-dose_phenomenon

    This postural hypotension usually happens shortly after the first dose is absorbed into the blood and can result in syncope (fainting). Syncope occurs in approximately 1% of patients given an initial dose of 2 mg prazosin or greater. This adverse effect is self-limiting and in most cases does not recur after the initial period of therapy or ...

  7. 18-year-old charged with fatally shooting man during ...

    www.aol.com/18-old-charged-fatally-shooting...

    An 18-year-old was arrested in connection to the fatal shooting of a man last month who was reportedly trying to sell his PlayStation 5. On Nov. 24, officers with the Houston Police Department ...

  8. Former Brooklyn Nets co-owner sues Citibank over shuttered ...

    www.aol.com/news/former-brooklyn-nets-co-owner...

    A former co-owner of the Brooklyn Nets who spent millions on his Citibank credit card claims the bank “unceremoniously dumped” him — and his 29 million “Thank You Points” worth $300,000.

  9. Alpha-1 blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_blocker

    The risk of first dose phenomenon may be reduced or eliminated by gradual-dose titration, since the adverse effects of Prazosin are dose-related. [7] This is also the case for Tamsulosin and it may be assumed that the others alpha-1 blockers work in a similar manner, since Tamsulosin is an alpha-1-a blocker and Prazosin is an alpha-1 blocker. [30]