Search results
Results from the WOW.Com Content Network
UVB-induced apoptosis is the programmed cell death of cells that become damaged by ultraviolet rays. This is notable in skin cells, to prevent melanoma . Some studies have shown that exercise accelerates this process.
Photoaging or photoageing [1] (also known as "dermatoheliosis" [2]) is a term used for the characteristic changes to skin induced by chronic UVA and UVB exposure. [ 3 ] : 29 Tretinoin is the best studied retinoid in the treatment of photoaging.
Lifetime cumulative UV exposure to skin is also responsible for significant age-associated dryness, wrinkling, elastin and collagen damage, freckling, IGH, age spots and other cosmetic changes. The American Academy of Dermatology advises that photoprotective measures be taken, including the use of sunscreen, whenever one is exposed to the sun ...
The sun is, by far, the greatest source of ultraviolet (UV) radiation, which is the culprit that causes most skin cancers—the most common form of cancer in the U.S. According to the Skin Cancer ...
Excessive UV radiation is the leading cause of (primarily) non-malignant skin tumors, [1] [2] which in extreme cases can be life-threatening. Sunburn is an inflammatory response in the tissue triggered by direct DNA damage by UV radiation. When the cells' DNA is overly damaged by UV radiation, type I cell-death is triggered and the tissue is ...
Cyclobutane pyrimidine dimers formed by adjacent thymine bases, or by adjacent cytosine bases, are frequent types of DNA damage induced by UV. [38] Human skin cells are capable of repairing most UV-induced damage by nucleotide excision repair, a process that protects against skin cancer, but may be inadequate at high levels of exposure. [38]
Actinic keratosis (AK), sometimes called solar keratosis or senile keratosis, [1] [2] is a pre-cancerous [3] area of thick, scaly, or crusty skin. [4] [5] Actinic keratosis is a disorder of epidermal keratinocytes that is induced by ultraviolet (UV) light exposure ().
All bands of UV radiation damage collagen fibers and accelerate aging of the skin. Both UVA and UVB destroy vitamin A in skin, which may cause further damage. [61] UVB radiation can cause direct DNA damage. [62] This cancer connection is one reason for concern about ozone depletion and the ozone hole.