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A placebo control group [3] [4] can be used to support a double-blind study, in which some subjects are given an ineffective treatment (in medical studies typically a sugar pill) to minimize differences in the experiences of subjects in the different groups; this is done in a way that ensures no participant in the experiment (subject or ...
Random assignment or random placement is an experimental technique for assigning human participants or animal subjects to different groups in an experiment (e.g., a treatment group versus a control group) using randomization, such as by a chance procedure (e.g., flipping a coin) or a random number generator. [1]
The independent variable of a study often has many levels or different groups. In a true experiment, researchers can have an experimental group, which is where their intervention testing the hypothesis is implemented, and a control group, which has all the same element as the experimental group, without the interventional element.
The simplest between-group design occurs with two groups; one is generally regarded as the treatment group, which receives the ‘special’ treatment (that is, it is treated with some variable), and the control group, which receives no variable treatment and is used as a reference (prove that any deviation in results from the treatment group ...
Control groups are a way of eliminating the possibility of incidental treatments being the cause of measured effects. The incidental treatments are controlled for. Compare treatment groups. A treatment that is only the absence of the manipulation being studied is simply one of the treatments and not a control, though it is now common to refer ...
The standard by which experimental observations are evaluated. In many clinical trials, one group of patients will be given an experimental drug or treatment, while the control group is given either a standard treatment for the illness or a placebo (NLM) Controlled clinical trial. A clinical study that includes a comparison (control) group.
In the statistical theory of design of experiments, randomization involves randomly allocating the experimental units across the treatment groups.For example, if an experiment compares a new drug against a standard drug, then the patients should be allocated to either the new drug or to the standard drug control using randomization.
Randomized clinical trials analyzed by the intention-to-treat (ITT) approach provide unbiased comparisons among the treatment groups. Intention to treat analyses are done to avoid the effects of crossover and dropout, which may break the random assignment to the treatment groups in a study. ITT analysis provides information about the potential ...