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A branched-chain amino acid (BCAA) is an amino acid having an aliphatic side-chain with a branch (a central carbon atom bound to three or more carbon atoms). Among the proteinogenic amino acids, there are three BCAAs: leucine, isoleucine, and valine. [1] Non-proteinogenic BCAAs include 2-aminoisobutyric acid and alloisoleucine. Leucine ...
In Corynebacterium glutamicum, BrnFE exports branched chain amino acids isoleucine, leucine, and valine, as well as methionine and homoserine. [3] [5] [8] The greatest induction of BrnFE expression occurs under high methionine concentrations, suggesting that methionine may actually be the native substrate rather than a branched-chain amino acid ...
The BCAT enzyme catalyzes the conversion of BCAAs and α-ketoglutarate into branched chain α-keto acids and glutamate. The structure to the right of branched chain amino acid aminotransferase was found using X-ray diffraction with a resolution of 2.20 Å. The branched-chain amino acid aminotransferase found in this image was isolated from ...
The amino acid-polyamine-organocation (APC) superfamily is the second largest superfamily of secondary carrier proteins currently known, [1] and it contains several Solute carriers. [ 2 ] [ 3 ] Originally, the APC superfamily consisted of subfamilies under the transporter classification number (TC # 2.A.3 ).
2-, alpha-, or α-amino acids [21] have the generic formula H 2 NCHRCOOH in most cases, [b] where R is an organic substituent known as a "side chain". [22] Of the many hundreds of described amino acids, 22 are proteinogenic ("protein-building").
It's been quite the week for cult fitness companies Equinox and SoulCycle after many customers cancelled their memberships and threatened to boycott both businesses indefinitely.
Branched chain amino acid transaminase 1 is a protein that in humans is encoded by the BCAT1 gene. [5] It is the first enzyme in the branched-chain amino acid ...
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