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2. PDE5 inhibitor - Wikipedia

   en.wikipedia.org/wiki/PDE5_inhibitor

   Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

3. Sildenafil - Wikipedia

   en.wikipedia.org/wiki/Sildenafil

   Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]

4. Can You Take Viagra With High Blood Pressure? - AOL

   www.aol.com/lifestyle/viagra-high-blood-pressure...

   Life-threatening problems can result when drug interactions between your daily medications cause side effects, and nowhere might that be more clear than with Viagra and high blood pressure ...

5. What Happens If You Take Viagra and You Don't Need It? - AOL

   www.aol.com/happens-viagra-dont-105800158.html

   There may be no serious side effects, or you may be at risk of damaging the blood vessels in your privates, creating dependency, or causing yourself heart problems. Using medications when anxious ...

6. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

   www.aol.com/viagra-treats-side-effects-plus...

   Likewise, Viagra shouldn’t be combined with antiretroviral drugs used to treat HIV/AIDS, as it can cause an increased concentration of sildenafil in the body. Breastfeeding women shouldn’t ...

7. Chronic kidney disease in cats - Wikipedia

   en.wikipedia.org/wiki/Chronic_kidney_disease_in_cats

   Cat with chronic kidney disease and typical symptoms: fatigue, emaciation and dull, shaggy coat. The chronic kidney disease of the cat (CKD or CNE) – also called chronic renal insufficiency (CRI or CNI) or chronic renal failure (CRF) in the older literature – is an incurable, progressive disease characterized by a gradual decrease in the nephrons and thus to a decreasing function ...

8. Got Headaches from Viagra or Cialis? Here's Why & How to Treat It

   www.aol.com/got-headaches-viagra-cialis-heres...

   In rare cases, Viagra and other ED medications may cause issues such as blurred vision, loss of vision, hearing loss, nasal congestion and feelings of dizziness or lightheadedness, indigestion or ...

9. Discovery and development of phosphodiesterase 5 inhibitors

   en.wikipedia.org/wiki/Discovery_and_development...

   Phosphodiesterase 5 is widely expressed in several tissues in the body for example brain, lung, kidney, urinary bladder, smooth muscle and platelets. [1] It is possible to prevent cGMP hydrolysis by inhibiting PDE5 and therefore treat diseases associated with low cGMP levels, because of this, PDE5 is an ideal target for the development of ...