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  2. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    CRISPR gene editing is a revolutionary technology that allows for precise, targeted modifications to the DNA of living organisms. Developed from a natural defense mechanism found in bacteria, CRISPR-Cas9 is the most commonly used system, that allows "cutting" of DNA at specific locations and either delete, modify, or insert genetic material.

  3. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    CRISPR has also been used to cure malaria in mosquitos, which could eliminate the vector and the disease in humans. [171] CRISPR may also have applications in tissue engineering and regenerative medicine, such as by creating human blood vessels that lack expression of MHC class II proteins, which often cause transplant rejection. [172]

  4. He Jiankui genome editing incident - Wikipedia

    en.wikipedia.org/wiki/He_Jiankui_genome_editing...

    On 26 November 2018, The CRISPR Journal published ahead of print an article by He, Ryan Ferrell, Chen Yuanlin, Qin Jinzhou, and Chen Yangran in which the authors justified the ethical use of CRISPR gene editing in humans. [74] As the news of CRISPR babies broke out, the editors reexamined the paper and retracted it on 28 December, announcing:

  5. Timeline of the history of genetics - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_the_history_of...

    2001: First draft sequences of the human genome are released simultaneously by the Human Genome Project and Celera Genomics. 2001: Francisco Mojica and Rudd Jansen propose the acronym CRISPR to describe a family of bacterial DNA sequences that can be used to specifically change genes within organisms.

  6. Regeneron to collaborate on gene editing therapies with ...

    www.aol.com/news/regeneron-collaborate-gene...

    CRISPR, discovered by Jennifer Doudna and CRISPR Therapeutics co-founder Emmanuelle Charpentier, uses molecular "scissors" to trim faulty parts of genes that can then be disabled or replaced with ...

  7. List of drugs by year of discovery - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_by_year_of...

    Discovered by Henry Hallett Dale, synthesized by Vincent du Vigneaud in 1952: ... In 2015 a simplified form of CRISPR edition was used in humans with Cas9, ...

  8. US FDA approves two gene therapies for sickle cell disease - AOL

    www.aol.com/news/us-approves-two-gene-therapies...

    The Vertex-CRISPR therapy has a U.S. list price of $2.2 million, while bluebird's is $3.1 million. Both therapies, pitched as one-time treatments, will be available in early 2024.

  9. Human germline engineering - Wikipedia

    en.wikipedia.org/wiki/Human_germline_engineering

    The researchers used tripronuclear (3PN) zygotes fertilized by two sperm and therefore non-viable, to investigate CRISPR/Cas9-mediated gene editing in human cells. The researchers found that while CRISPR/Cas9 could effectively cleave the β-globin gene , the efficiency of homologous recombination directed repair of CRISPR/Cas9 was inefficient ...