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Vitamin B 12 is derived from a tetrapyrrolic structural framework created by the enzymes deaminase and cosynthetase which transform aminolevulinic acid via porphobilinogen and hydroxymethylbilane to uroporphyrinogen III. The latter is the first macrocyclic intermediate common to heme, chlorophyll, siroheme and B 12 itself.
Vitamin B 12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5]
Vitamin B12 deficiency is rare, but low or marginal levels are common, affecting up to 40% of Western populations. A new study has found that, in older people, both lower and higher levels of ...
The structure of vitamin B 12 was the first low-molecular weight natural product determined by x-ray analysis rather than by chemical degradation. Thus, while the structure of this novel type of complex biomolecule was established, its chemistry remained essentially unknown; exploration of this chemistry became one of the tasks of the vitamin's chemical synthesis.
Vitamin B12 is important for processing that sugar into energy,” explains Amit Sachdev, MD, MS, medical director in the Department of Neurology at Michigan State University. “Low B12 levels ...
What does vitamin B12 do? Vitamin B12, according to the National Institutes of Health Office of Dietary Supplements, is a nutrient (or family of molecules called the cobalmins that incorporate an ...
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