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  2. Eosinophilic fasciitis - Wikipedia

    en.wikipedia.org/wiki/Eosinophilic_fasciitis

    Eosinophilic fasciitis (/ ˌ iː ə ˌ s ɪ n ə ˈ f ɪ l ɪ k ˌ f æ ʃ i ˈ aɪ t ɪ s, ˌ iː oʊ-,-ˌ f æ s i-/ [2] [3]), also known as Shulman's syndrome, [4] is an inflammatory disease that affects the fascia, other connective tissues, surrounding muscles, blood vessels and nerves.

  3. Activated PI3K delta syndrome - Wikipedia

    en.wikipedia.org/wiki/Activated_PI3K_Delta_Syndrome

    PI3kinase. The pathophysiology of activated PI3K delta syndrome has several aspects. [2] The normal function has P110δ (PI3K) involved in immune system regulation. [9]P110δ effect is not limited to the immune system; P110δ has a presence in transformed epithelial cells and cell adhesion molecules (airway inflammation), and research has been done on the possibility of P110δ in the nervous ...

  4. Drusen - Wikipedia

    en.wikipedia.org/wiki/Drusen

    Laser treatment of drusen has been studied. While it is possible to eliminate drusen with this treatment strategy, it has been shown that this fails to reduce the risk of developing the choroidal neovascularisation which causes the blindness associated with age-related macular degeneration. [15]

  5. Plantar fibromatosis - Wikipedia

    en.wikipedia.org/wiki/Plantar_fibromatosis

    Palmar fibromatosis 10-65% of the time. [7] Peyronie's disease [8] Epilepsy patients [6] Diabetes mellitus [8] There is also a suspected, although unproven, link between incidence and alcoholism, smoking, liver diseases, thyroid problems, and stressful work involving the feet. [citation needed]

  6. Camurati–Engelmann disease - Wikipedia

    en.wikipedia.org/wiki/Camurati–Engelmann_disease

    Camurati–Engelmann disease (CED) is a very rare autosomal dominant genetic disorder that causes characteristic anomalies in the skeleton. It is also known as progressive diaphyseal dysplasia. It is a form of dysplasia. [3] Patients typically have heavily thickened bones, especially along the shafts of the long bones (called diaphyseal dysplasia).

  7. Pycnodysostosis - Wikipedia

    en.wikipedia.org/wiki/Pycnodysostosis

    [10] Pycnodysostosis also causes problems that may become evident with time. Aside from the broken bones, the distal phalanges and the collar bone can undergo slow progressive deterioration. Vertebral defects may permit the spine to curve laterally resulting in scoliosis. The dental problems often require orthodontic care and cavities are common.

  8. Eumycetoma - Wikipedia

    en.wikipedia.org/wiki/Eumycetoma

    Eumycetoma, also known as Madura foot, [1] [6] is a persistent fungal infection of the skin and the tissues just under the skin, affecting most commonly the feet, although it can occur in hands and other body parts. [5]

  9. Sinus tarsi syndrome - Wikipedia

    en.wikipedia.org/wiki/Sinus_tarsi_syndrome

    Sinus tarsi syndrome can have a variety of causes. The most common is an inversion (rolling out) ankle sprain, which makes up 70-80% of cases, followed by pronation of the foot, which is responsible for about 20-30% of cases. [3] More rarely, excessive physical activity and other forms of foot trauma/chronic ankle injury are thought to be the ...