Ads
related to: how is oxidative stress caused
Search results
Results from the WOW.Com Content Network
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]
But under oxidative stress conditions, excessive ROS can damage cellular proteins, lipids and DNA, leading to fatal lesions in the cell that contribute to carcinogenesis. Cancer cells exhibit greater ROS stress than normal cells do, partly due to oncogenic stimulation, increased metabolic activity and mitochondrial malfunction.
Oxidative free radicals, such as the hydroxyl radical and the superoxide radical, can cause DNA damages, and such damages have been proposed to play a key role in the aging of crucial tissues. [20] DNA damage can result in reduced gene expression, cell death and ultimately tissue dysfunction. [20]
Research suggests that oxidative stress, which is caused by factors including sunlight, alcohol, and certain medications, plays a role in aging and the development of neurodegenerative diseases.
Cellular stress response is the wide range of molecular changes that cells undergo in response to environmental stressors, including extremes of temperature, exposure to toxins, and mechanical damage. Cellular stress responses can also be caused by some viral infections. [1]
"This can cause leaky gut syndrome and increase inflammation and oxidative stress," says Alexander. She adds that inflammation and oxidative stress interfere with your hypothalamus, ...
XthA (exonuclease III, a DNA repair enzyme) and KatE (catalase) are known to play important roles in the defense against oxidative stress but KatF regulon genes are not induced by oxidative stress. [2] There is an overlap between oxidative stress response and other regulatory networks like heat shock response, SOS response.
Eating too much added sugar causes traffic jams inside cells that can eventually lead to chronic diseases like diabetes. ... who studies the role of oxidative stress in cancer said the research ...
Ads
related to: how is oxidative stress caused