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The Reproducibility Project is a series of crowdsourced collaborations aiming to reproduce published scientific studies, finding high rates of results which could not be replicated. It has resulted in two major initiatives focusing on the fields of psychology [ 1 ] and cancer biology. [ 2 ]
Databases for oncogenomic research are biological databases dedicated to cancer data and oncogenomic research. They can be a primary source of cancer data, offer a certain level of analysis (processed data) or even offer online data mining .
Results from The Reproducibility Project: Cancer Biology suggest most studies of the cancer research sector may not be replicable. In a 2012 paper, C. Glenn Begley , a biotech consultant working at Amgen , and Lee Ellis, a medical researcher at the University of Texas, found that only 11% of 53 pre-clinical cancer studies had replications that ...
The Cancer Genome Anatomy Project (CGAP), created by the National Cancer Institute (NCI) in 1997 and introduced by Al Gore, is an online database on normal, pre-cancerous and cancerous genomes. It also provides tools for viewing and analysis of the data, allowing for identification of genes involved in various aspects of tumor progression.
Pan-cancer studies aim to detect the genes whose mutation is conducive to oncogenesis, as well as recurrent genomic events or aberrations between different tumors.For these studies, it is necessary to standardize the data between multiple platforms, establishing criteria between different researchers to work on the data and present the results.
Welcome to WikiProject Biology, a WikiProject for discussing biology-related articles, editing issues, projects, and guidelines.The purpose of this project is to provide common ground for editors working in all biology-related projects, for seeking advice or requesting help from a broader community of biology editors, and for coordinating the categorization of biology articles.
The Network of Cancer Genes (NCG) is a freely accessible web resource of genes that, when altered in their sequence, drive clonal expansion of normal tissues (healthy drivers) or cancer (cancer drivers). The project was launched in 2010 and has reached its 7th release in 2022.
The goals of the project are to help sequence and catalog different cancer genomes. Beyond just sequencing the project's internal partners each have different areas of focus that will assist in the project's overall goal of determining unique ways for early detection of cancer, better prevention, and improved treatment for patients. [1]