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Non-specific immunity, or innate immunity, is the immune system with which you were born, made up of phagocytes and barriers. Phagocytosis , derived from the Greek words phagein , meaning to eat, kytos or cell, and “osis” meaning process, was first described by Élie Metchnikoff , who won the Nobel Prize 100 years ago.
The innate immune system or nonspecific immune system [1] is one of the two main immunity strategies in vertebrates (the other being the adaptive immune system). The innate immune system is an alternate defense strategy and is the dominant immune system response found in plants , fungi , prokaryotes , and invertebrates (see Beyond vertebrates ).
The behavioral immune system is a phrase coined by the psychological scientist Mark Schaller to refer to a suite of psychological mechanisms that allow individual organisms to detect the potential presence of infectious parasites or pathogens in their immediate environment, and to engage in behaviors that prevent contact with those objects and individuals.
In all vertebrates, there are two different kinds of immunities: Innate and Adaptive immunity. Innate immunity is used to fight off non-changing antigens and is therefore considered nonspecific. It is usually a more immediate response than the adaptive immune system, usually responding within minutes to hours. [2]
The immune system is involved in many aspects of physiological regulation in the body. The immune system interacts intimately with other systems, such as the endocrine [83] [84] and the nervous [85] [86] [87] systems. The immune system also plays a crucial role in embryogenesis (development of the embryo), as well as in tissue repair and ...
Intrinsic immunity refers to a set of cellular-based anti-viral defense mechanisms, notably genetically encoded proteins which specifically target eukaryotic retroviruses. Unlike adaptive and innate immunity effectors, intrinsic immune proteins are usually expressed at a constant level, allowing a viral infection to be halted quickly.
The immune system's response to a few diseases, such as dengue, counterproductively worsens the next infection (antibody-dependent enhancement). [ 8 ] As of 2019, researchers are still trying to find out why some vaccines produce life-long immunity, while the effectiveness of other vaccines drops to zero in less than 30 years (for mumps) or ...
Rather, non-specific effects represent a form of general immunomodulation, with important consequences for the immune system's ability to handle subsequent challenges. It is estimated that millions of child deaths in low income countries could be prevented every year if the non-specific effects of vaccines were taken into consideration in ...