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The rationale behind using inhaled corticosteroids and formoterol combination therapy as a reliever as opposed to salbutamol, a short-acting β2-adrenergic agonist, is that this dosage regimen shows a reduction in the severe asthma exacerbation risk compared with using β2-adrenergic agonists reliever.
“Inhaled corticosteroids are considered the gold standard for treatment of persistent asthma,” says Dr. Bowser. Corticosteroids are a type of anti-inflammatory drug. Your body naturally makes ...
[2] [3] [4] It is used in the management of asthma and chronic obstructive pulmonary disease (COPD). [4] It is used by inhaling the medication into the lungs. [4] Common side effects include thrush, headache, and cough. [5] Serious side effects may include worsening asthma, anaphylaxis, seizures, and heart problems. [5]
Budesonide/formoterol, sold under the brand name Symbicort among others, is a fixed-dose combination medication used in the management of asthma or chronic obstructive pulmonary disease (COPD). [2] It contains budesonide, a steroid; and formoterol, a long-acting β 2-agonist (LABA). [2]
Fluticasone propionate, sold under the brand names Flovent and Flonase among others, is a glucocorticoid steroid medication. [8] When inhaled it is used for the long term management of asthma and COPD. [8] In the nose it is used for hay fever and nasal polyps. [9] [10] It can also be used for mouth ulcers. [11] It works by decreasing inflammation.
Corticosteroids, specifically glucocorticoids, are anti-inflammatory agents used to treat allergic conditions. Corticosteroids can be classified into mineralocorticoids , which regulate salt and water balances, and glucocorticoids that play a role in glucose homeostasis and regulating the activation of immune cells.
There are two main types of corticosteroids: glucocorticoids and mineralocorticoids. Glucocorticoids, such as cortisol, are involved in regulating metabolism and suppressing inflammation. They have anti-inflammatory and immunosuppressive properties, making them useful in the treatment of conditions like asthma, arthritis, and autoimmune diseases.
It is the first asthma triple-combination therapy; it consists of a fixed-dose combination of three active substances (indacaterol, glycopyrronium bromide and mometasone furoate) in capsules, to be administered using an inhaler. [11]
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