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Isopropyl β-d-1-thiogalactopyranoside (IPTG) is a molecular biology reagent. This compound is a molecular mimic of allolactose , a lactose metabolite that triggers transcription of the lac operon , and it is therefore used to induce protein expression where the gene is under the control of the lac operator .
When you have high blood pressure, your heart and blood vessels have to work harder to make blood flow through your body. This is pretty much the opposite of what sildenafil does — as a reminder ...
For example, problems with both your privates and your heart can be associated with a vascular condition that affects blood flow. PDE5 inhibitors like sildenafil may not be safe for people who ...
Viagra could lead to more serious side effects, such as: Priapism (a painful, long-lasting arousal) Vision loss. Chest pain. Flu-like symptoms. Heart attack. Stroke. Dizziness. Sudden low blood ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
The capillary blood flow velocity also increased in each individual patient and the mean capillary flow velocity of all patients increased significantly. These results came without significant reductions of the systemic blood pressure. [7] However, the therapeutic effects of PDE5 inhibitors in primary (idiopathic) RP are less well defined. [3]
Viagra can help reduce blood pressure in the lungs within its role as a vasodilator — essentially, it can do for your lungs what it does for your privates. Sildenafil lowers blood pressure in ...
IPTG is a reagent which mimics the structure of allolactose, and can therefore bind to the lac repressor and prevent it from inhibiting gene expression. Once enough IPTG is added, the T7 gene is normally transcribed and so transcription of the gene of interest downstream of the T7 promoter also begins. [6]