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Androgen insensitivity syndrome (AIS) is a condition involving the inability to respond to androgens, typically due to androgen receptor dysfunction. [ 1 ] It affects 1 in 20,000 to 64,000 XY ( karyotypically male) births.
Complete androgen insensitivity syndrome (CAIS) is an AIS condition that results in the complete inability of the cell to respond to androgens. [1] [2] [3] As such, the insensitivity to androgens is only clinically significant when it occurs in individuals who are exposed to significant amounts of testosterone at some point in their lives. [1]
Mild androgen insensitivity syndrome (MAIS) is an intersex variation that results in a mild impairment of the cell's ability to respond to androgens. [1] [2] [3] The degree of impairment is sufficient to impair spermatogenesis and / or the development of secondary sexual characteristics at puberty in males, but does not affect genital differentiation or development.
Low testosterone or testosterone deficiency, also known as hypogonadism, is a condition in which patients develop symptoms. ... reduced insulin sensitivity, impaired glucose control, and high ...
More specifically, androgenetic alopecia is caused by a genetic sensitivity to an androgen called DHT. Your body creates DHT as a byproduct of testosterone, the main androgen hormone in the male ...
Low testosterone affects almost 40 percent of men aged 45 and older, though Dr. Lipshultz says it’s rare for low T to cause genital numbness or lessened sensitivity. Testosterone levels vary ...
Right, Habitus after 3.5 years of androgen treatment. [17] Partial androgen insensitivity syndrome is diagnosed when the degree of androgen insensitivity in an individual with a 46,XY karyotype is great enough to partially prevent the masculinization of the genitalia, but is not great enough to completely prevent genital masculinization.
The androgen receptor (AR), also ... repeats leads to increased receptor sensitivity to circulating androgens and more repeats leads to decreased receptor sensitivity.