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There are two types of active transport: primary active transport that uses adenosine triphosphate (ATP), and secondary active transport that uses an electrochemical gradient. This process is in contrast to passive transport , which allows molecules or ions to move down their concentration gradient, from an area of high concentration to an area ...
Both channels and pumps are ion transporters which move ions across membranes. Channels move ions quickly, through passive transport, down electrical and concentration gradients (moving "downhilll"); whereas pumps move ions slowly, through active transport, building-up gradients (moving "uphill"). [10]
Neurotransmitter transporters are a class of membrane transport proteins that span the cellular membranes of neurons. Their primary function is to carry neurotransmitters across these membranes and to direct their further transport to specific intracellular locations. There are more than twenty types of neurotransmitter transporters.
6531 13162 Ensembl ENSG00000142319 ENSG00000276996 ENSMUSG00000021609 UniProt Q01959 Q61327 RefSeq (mRNA) NM_001044 NM_010020 RefSeq (protein) NP_001035 NP_034150 Location (UCSC) Chr 5: 1.39 – 1.45 Mb Chr 13: 73.68 – 73.73 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The dopamine transporter (DAT, also sodium-dependent dopamine transporter) is a membrane-spanning protein coded ...
6572 20508 Ensembl ENSG00000187714 ENSMUSG00000100241 UniProt Q16572 O35304 Q3TYJ1 RefSeq (mRNA) NM_003055 NM_021712 RefSeq (protein) NP_003046 NP_068358 Location (UCSC) Chr 10: 49.61 – 49.61 Mb Chr 14: 32.18 – 32.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The Vesicular acetylcholine transporter (VAChT) is a neurotransmitter transporter which is responsible for loading ...
GLUT1 deficiency syndrome, also known as GLUT1-DS, De Vivo disease or Glucose transporter type 1 deficiency syndrome, is an autosomal dominant genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier. [1]
Amino acid transport disorders are medical conditions associated with a failure of amino acids to be absorbed from the kidney or intestine. [citation needed]
This disorder disrupts the carnitine shuttle system from moving fatty acids across the mitochondrial membrane, leading to a decrease in fatty acid catabolism. The result is an accumulation of fatty acid within muscles and liver, decreased tolerance to long term exercise, inability to fast for more than a few hours, muscle weakness and wasting ...