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Another method for drug discovery is de novo drug design, in which a prediction is made of the sorts of chemicals that might (e.g.) fit into an active site of the target enzyme. For example, virtual screening and computer-aided drug design are often used to identify new chemical moieties that may interact with a target protein.
Crown Bioscience is a company that offers a range of preclinical and translational drug research and development platforms and services. These include in vivo, in vitro, ex vivo patient derived xenograft (PDX), cell line derived xenograft (CDX), organoids and 3D models, as well as oncology databases, biomarker, bioanalysis and bioinformatics services.
Caliper's Discovery Alliances & Services division (CDAS) was created from the acquisitions of NovaScreen, a provider of in vitro & in vivo discovery services. The in vitro service arm of CDAS included in vitro drug discovery and development, including screening assays to define the mode of action, side effect profiles, selectivity, and other relevant activities of drug candidates.
Syntekabio Co., Ltd. (KOSDAQ: 226330) is a drug discovery company bringing together biology and AI/ML since 2009 and facilitating the discovery of first-in-class and best-in-class compounds, rapidly. The Company has its own supercomputer cloud, along with a global contract research organization network to complement and validate its ...
Curia (formerly AMRI or Albany Molecular Research Inc. [2]) is a contract research and manufacturing organization that provides drug discovery, development, cGMP manufacturing and aseptic fill and finish to the pharmaceutical and biotechnology industries.
In May 2023, Recursion acquired two companies in the AI-enabled drug discovery space, Toronto-headquartered Cyclica and Montreal-based Valence. [ 24 ] [ 25 ] In July 2023, the company announced a collaboration and $50M investment from NVIDIA to accelerate the development of its AI foundation models for biology and chemistry , and potentially ...
From 2008 to 2013, Charles River acquires several companies including NewLab Bioquality AG, [14] MIR Preclinical Services, [15] Piedmont Research Center, LLC, [16] Cerebricon, Ltd., Accugenix, and Vital River, allowing the company to expand their research models and services portfolio to drug development and discovery markets in China.
Schrödinger, Inc. is an international scientific software and biotechnology company that specializes in developing computational tools and software for drug discovery and materials science. Schrödinger's software is used by pharmaceutical companies , biotech firms, and academic researchers to simulate and model the behavior of molecules at ...
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