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  2. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 to 30 minutes. As with most prescription ...

  3. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil. Thus, the metabolite is responsible for about 20% of sildenafil's action. Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and to a lesser extent in the urine (around 13% of the administered oral dose).

  4. What Happens If You Take 2 Viagra In 24 Hours? - AOL

    www.aol.com/happens-2-viagra-24-hours-135700769.html

    Sildenafil citrate, the active ingredient in Viagra, is a PDE5 inhibitor. Phosphodiesterase type 5 is an enzyme that’s found in the smooth muscle cells of blood vessels and helps regulate blood ...

  5. What Happens If You Take Viagra and You Don't Need It? - AOL

    www.aol.com/happens-viagra-dont-105800158.html

    October 25, 2024 at 6:58 AM. ... long-lasting arousal) Vision loss. Chest pain. Flu-like symptoms. ... Last but not least, using Viagra when you don’t have ED brings the risk of poisoning.

  6. Talk:Sildenafil/Archive 2 - Wikipedia

    en.wikipedia.org/wiki/Talk:Sildenafil/Archive_2

    The page currently states: "Onset is typically within 20 minutes and lasts for about 2 hours.[8] A dose of 25-100 mg should be taken four hours prior to activity." It can be corrected as follows: "Onset of action is typically within 20 minutes. The effects last for an average of 2 hours.

  7. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

    www.aol.com/4-common-ed-pills-weighing-141800609...

    Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world. These little pills have helped hundreds of millions of men get hard and ...

  8. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  9. What Is the Safest ED Medication? - AOL

    www.aol.com/safest-ed-medication-105700669.html

    The active ingredient in Viagra, sildenafil provides relief from ED for around four hours per dose. Tadalafil . The active ingredient in Cialis, tadalafil is a long-lasting medication that can ...

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