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  2. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    An opioid overdose is toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone. [3] [5] This preventable pathology can be fatal if it leads to respiratory depression, a lethal condition that can cause hypoxia from slow and shallow breathing. [3]

  3. Opioid withdrawal - Wikipedia

    en.wikipedia.org/wiki/Opioid_withdrawal

    Opioid use triggers a rapid adaptation in cellular signaling pathways that, when reduced or stopped, can cause adverse physiological effects. All opioids, both recreational drugs and medications , when reduced or stopped, can lead to opioid withdrawal symptoms.

  4. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    And more than 400,000 go to an emergency room for that reason.” Clinics that dispensed painkillers proliferated with only the loosest of safeguards, until a recent coordinated federal-state crackdown crushed many of the so-called “pill mills.” As the opioid pain meds became scarce, a cheaper opioid began to take over the market — heroin.

  5. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    Opioid replacement therapy (ORT), also known as opioid substitution therapy (OST) or Medications for Opioid Use Disorder (MOUD), involves replacing an opioid, such as heroin. [ 110 ] [ 111 ] Commonly used drugs for ORT are methadone and buprenorphine/naloxone ( Suboxone ), which are taken under medical supervision. [ 111 ]

  6. 350 Miles Away - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    Toby Fischer lives in South Dakota, where just 27 doctors are certified to prescribe buprenorphine -- a medication that blunts the symptoms of withdrawal from heroin and opioid painkillers. A Huffington Post analysis of government data found nearly half of all counties in America don't have such a certified physician. So every month, Fischer and his mother drive to Colorado to pick up their ...

  7. Hypoventilation - Wikipedia

    en.wikipedia.org/wiki/Hypoventilation

    By definition it causes an increased concentration of carbon dioxide (hypercapnia) and respiratory acidosis. Hypoventilation is not synonymous with respiratory arrest , in which breathing ceases entirely and death occurs within minutes due to hypoxia and leads rapidly into complete anoxia , although both are medical emergencies.

  8. Opioid-induced hyperalgesia - Wikipedia

    en.wikipedia.org/wiki/Opioid-induced_hyperalgesia

    Tolerance, another condition that can arise from prolonged exposure to opioids, can often be mistaken for opioid-induced hyperalgesia and vice versa, as the clinical presentation can appear similar. Although tolerance and opioid-induced hyperalgesia both result in a similar need for dose escalation to receive the same level of effect to treat ...

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