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"Sociobiology is now part of the core research and curriculum of virtually all biology departments, and it is a foundation of the work of almost all field biologists. " Sociobiological research on nonhuman organisms has increased dramatically and continuously in the world's top scientific journals such as Nature and Science .
The term "biological target" is frequently used in pharmaceutical research to describe the native protein in the body whose activity is modified by a drug resulting in a specific effect, which may be a desirable therapeutic effect or an unwanted adverse effect. In this context, the biological target is often referred to as a drug target.
Protein targeting or protein sorting is the biological mechanism by which proteins are transported to their appropriate destinations within or outside the cell. [ 1 ] [ 2 ] [ note 1 ] Proteins can be targeted to the inner space of an organelle , different intracellular membranes , the plasma membrane , or to the exterior of the cell via secretion .
The identification of target proteins, the investigation of signal transduction processes and the understanding of their interaction with ligands are key elements of modern biomedical research. Since the interaction with target proteins is the molecular origin of most drugs , their particular importance for molecular biology , molecular ...
Social selection is a term used with varying meanings in biology. Joan Roughgarden proposed a hypothesis called social selection as an alternative to sexual selection. Social selection is argued to be a mode of natural selection based on reproductive transactions and a two-tiered approach to evolution and the development of social behavior. [1]
Target selection is the process by which axons (nerve fibres) selectively target other cells for synapse formation. Synapses are structures which enable electrical or chemical signals to pass between nerves.
In developmental biology, 'morphogen' is rigorously used to mean a signalling molecule that acts directly on cells (not through serial induction) to produce specific cellular responses that depend on morphogen concentration. This definition concerns the mechanism, not any specific chemical formula, so simple compounds such as retinoic acid (the ...
Akt target substrates contain a minimum consensus sequence R-X-R-X-X-[Ser/Thr]-Hyd, where Hyd is a hydrophobic amino acid, although other factors such as sub-cellular localisation and 3-dimensional structure are important. [5] Phosphorylation by Akt can be inhibitory or stimulatory, either suppressing or enhancing the activity of target proteins.