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First-line choices for medications include SSRIs or SNRIs to treat generalized anxiety disorder, social anxiety disorder or panic disorder. [ 7 ] [ 72 ] [ 82 ] For adults, there is no good evidence supporting which specific medication in the SSRI or SNRI class is best for treating anxiety, so cost often drives drug choice.
Both of them are considered as first-line anti-anxiety medications. TCAs are second-line treatment as they cause more significant adverse effects when compared to the first-line treatment. Benzodiazepines are effective in emergent and short-term treatment of anxiety disorders due to their fast onset but carry the risk of dependence. [4]
In Canada, SSRIs are a first-line treatment of adult obsessive–compulsive disorder (OCD). In the UK, they are first-line treatment only with moderate to severe functional impairment and as second line treatment for those with mild impairment, though, as of early 2019, this recommendation is being reviewed. [26]
The first line of treatment for social anxiety disorder is cognitive behavioral therapy (CBT). [9] Medications such as SSRIs are effective for social phobia, especially paroxetine . [ 10 ] [ 11 ] [ non-primary source needed ] CBT is effective in treating this disorder, whether delivered individually or in a group setting. [ 12 ]
SSRIs were the first drugs to establish a theoretical pathophysiological role for 5-HT in affective illnesses and in the broad spectrum of anxiety disorders. Likewise, they were the first to confirm the inhibition of neurotransmitter re-uptake as an important therapeutic principle. [1] [8] The SSRIs are the first rationally designed class of ...
SSRIs are used as a first-line treatment for social anxiety, but they do not work for everyone. One alternative would be venlafaxine , an SNRI , which has shown benefits for social phobia in five clinical trials against a placebo, while the other SNRIs are not considered particularly useful for this disorder as many of them did not undergo ...
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