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The mechanism of how exactly pressure therapy works is unknown at present, but many patients with keloid scars and lesions have benefited from it. [7] Intralesional injection with a corticosteroid such as triamcinolone acetonide (Kenalog) does appear to aid in the reduction of fibroblast activity, inflammation and pruritus. [17]
The exact mechanism of action of silicone gel sheeting has not been fully studied. Currently, many proposed mechanisms explain the efficacy of such treatment, including the occlusion and hydration effect, increased body surface temperature, polarized electric charge, immunological effects, etc. [9] The occlusion and hydration effect is the most studied mechanism of action.
Atypical mole removal is performed when moles look dysplastic, as this is associated with an increased risk of melanoma; Cosmetic mole removal is performed when moles are non-cancerous, but are preferred to be eliminated due to aesthetic or practical considerations. [25] Shave excision is the most frequently used method for mole removal.
Hypertrophic scarring is a common development in wounds that take longer than two or three weeks to heal. This frequently happens weeks after the wound was closed. If compression is applied as soon as the wound heals and is kept at a pressure of about 24 mm Hg, raised scarring can be avoided.
A series of injections with triamcinolone acetonide or another corticosteroid may reduce keloid size and irritation. It is used as a preinductor and/or inductor of birth in cows. It was also used in the horse racing industry, but it is now a banned substance if found in a horse's system on race day. [29]
A 2006 clinical trial found no statistically significant change in hypertrophic scar appearance from products of this type compared to the standard petrolatum emollient. [6] According to a 2011 Los Angeles Times article, "there were just two randomized comparison trials of Mederma, with a combined total of 38 participants. Neither trial found ...
A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings , cuts and burns.
Hypertrophic scars occur when the body overproduces collagen, which causes the scar to be raised above the surrounding skin. Hypertrophic scars take the form of a red raised lump on the skin for lighter pigmented skin and the form of dark brown for darker pigmented skin. They usually occur within 4 to 8 weeks following wound infection or wound ...
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