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Hypertrophic scar. Silicone gel sheeting is the gold-standard and non-invasive treatment for hypertrophic and keloid scars. During skin injury repair, dermal cells proliferate and migrate from the skin tissue to the wound, producing collagen and causing contraction of the placement dermis. [5]
Intralesional corticosteroid injections were introduced as a treatment in the mid-1960s as a method to attenuate scarring. [25] Pressure therapy has been used for prophylaxis and treatment of keloids since the 1970s. [25] Topical silicone gel sheeting was introduced as a treatment in the early 1980s. [25]
Laser-assisted drug delivery (LADD) is a drug delivery technique commonly used in the dermatology field that involves lasers. As skin acts as a protective barrier to the environment, the absorption of topical products through the epidermis is limited; thus, different drug delivery modalities have been employed to improve the efficacy of these treatments.
Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, [13] to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions.
A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings , cuts and burns.
A long-term course of corticosteroid injections into the scar may help flatten and soften the appearance of keloid or hypertrophic scars. [54] Topical steroids are ineffective. [55] However, clobetasol propionate can be used as an alternative treatment for keloid scars. [56]
Depending on scar type, treatment may be invasive (intralesional steroid injections, surgery) and/or conservative (compression therapy, topical silicone gel, brachytherapy, photodynamic therapy). [82]
This process can take many hours, and often requires repeated removal of scabs for best visibility of the scars. [6] Packing An inert material such as clay or ash is packed into the wound; massive hypertrophic scars are formed during healing as the wound pushes out the substance that had been inserted into the wound. [18]
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