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  2. Multidrug-resistant Gram-negative bacteria - Wikipedia

    en.wikipedia.org/wiki/Multidrug-resistant_gram...

    Multidrug resistant Gram-negative bacteria (MDRGN bacteria) are a type of Gram-negative bacteria with resistance to multiple antibiotics. They can cause bacteria infections that pose a serious and rapidly emerging threat for hospitalized patients and especially patients in intensive care units . [ 1 ]

  3. Gram-negative bacteria - Wikipedia

    en.wikipedia.org/wiki/Gram-negative_bacteria

    Gram-negative bacteria are bacteria that, unlike gram-positive bacteria, do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. [1] Their defining characteristic is their cell envelope , which consists of a thin peptidoglycan cell wall sandwiched between an inner ( cytoplasmic ) membrane and an ...

  4. Carbapenem-resistant enterobacteriaceae - Wikipedia

    en.wikipedia.org/wiki/Carbapenem-resistant_enter...

    Carbapenem-resistant Enterobacteriaceae (CRE) or carbapenemase-producing Enterobacteriaceae (CPE) are gram-negative bacteria that are resistant to the carbapenem class of antibiotics, considered the drugs of last resort for such infections. They are resistant because they produce an enzyme called a carbapenemase that disables the drug molecule ...

  5. Carbapenem - Wikipedia

    en.wikipedia.org/wiki/Carbapenem

    Infections caused by the non-fermenting gram-negative bacteria Pseudomonas aeruginosa and Acinetobacter baumanni are most commonly encountered in hospitalized people. These bacteria exhibit an unusually high level of intrinsic resistance to antibiotics due to their expression of a wide range of resistance mechanisms.

  6. ESKAPE - Wikipedia

    en.wikipedia.org/wiki/ESKAPE

    The Gram-negative aspects of the membrane surface of A. baumannii, including the efflux pump and outer membrane, affords it a wider range of antibiotic resistance. [14] Additionally, some problematic A. baumannii strains are able to acquire families of efflux pumps from other species, and are commonly first to develop new β-lactamases to ...

  7. Multidrug-resistant bacteria - Wikipedia

    en.wikipedia.org/wiki/Multidrug-resistant_bacteria

    A variety of different bacteria - testing for antimicrobial resistance. Multidrug-resistant bacteria (MDR bacteria) are bacteria that are resistant to three or more classes of antimicrobial drugs. [1] MDR bacteria have seen an increase in prevalence in recent years [clarification needed] [2] and pose serious risks to public health.

  8. Infection breakthrough as 80-year-old antibiotic may be ...

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  9. Cephalosporin - Wikipedia

    en.wikipedia.org/wiki/Cephalosporin

    Gram-negative: Fourth-generation cephalosporins are zwitterions that can penetrate the outer membrane of Gram-negative bacteria. [32] They also have a greater resistance to β-lactamases than the third-generation cephalosporins. Many can cross the blood–brain barrier and are effective in meningitis. They are also used against Pseudomonas ...