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In December 2013, the government of India, in response to rising recreational use and the use of ketamine as a date rape drug, added it to Schedule X of the Drug and Cosmetics Act requiring a special license for sale and maintenance of records of all sales for two years. [150] [151]
Ketamine and MDMA were the most common ingredients in Argentina in 2019, however "tuci" samples have since shown batch variation based on country and year. In some countries the samples were adulterated with anesthetics or prescription opioids, and other substances like methamphetamine and caffeine , and other substances. [ 2 ]
After the publication of the NIH-run antidepressant clinical trial, clinics began opening in which the intravenous ketamine is given for depression. [5] [6] This practice is an off label use of IV ketamine in the United States, though the intranasal version of esketamine has been approved by the FDA for treatment of depression [5] [7] In 2015 there were about 60 such clinics in the US; the ...
Here, we explore ketamine therapy’s safety with Steven L. Mandel, M.D., co-founder of Ketamine Clinics Los Angeles and the founder of the nonprofit American Society of Ketamine Physicians ...
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NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [5] [13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.