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Ulcerative colitis is an autoimmune disease characterized by T-cells infiltrating the colon. [43] No direct causes for UC are known, but factors such as genetics, environment, and an overactive immune system play a role. [1] UC is associated with comorbidities that produce symptoms in many areas of the body outside the digestive system.
The signs and symptoms of colitis are quite variable and dependent on the cause of the given colitis and factors that modify its course and severity. [2]Common symptoms of colitis may include: mild to severe abdominal pains and tenderness (depending on the stage of the disease), persistent hemorrhagic diarrhea with pus either present or absent in the stools, fecal incontinence, flatulence ...
Depending on the cause of the inflammation, symptoms may last from one day to more than a week. Gastroenteritis caused by viruses may last one to two days. Most people recover easily from a short episode of vomiting and diarrhea by drinking clear fluids to replace the fluid that was lost and then gradually progressing to a normal diet.
It has also been observed to cause villus ischemia, and increase intestinal motility. [15] The net result of these changes is induced diarrhoea. [15] Enteritis necroticans is an often fatal illness, caused by β-toxin of Clostridium perfringens. [16] This causes inflammation and segments of necrosis throughout the gastrointestinal tract.
Enterocolitis is an inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon. [1] It may be caused by various infections, with bacteria, viruses, fungi, parasites, or other causes.
Pancolitis or universal colitis, in its most general sense, refers to inflammation of the entire large intestine comprising the cecum, ascending, transverse, descending, sigmoid colon and rectum. It can be caused by a variety of things such as inflammatory bowel disease , more specifically a severe form of ulcerative colitis .
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The ingestion of one viable cyst may cause an infection. [12] Steroid therapy can occasionally provoke severe amoebic colitis in people with any E. histolytica infection. [13] This bears high mortality: on average more than 50% with severe colitis die. [13]
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