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Ulcerative colitis is an autoimmune disease characterized by T-cells infiltrating the colon. [43] No direct causes for UC are known, but factors such as genetics, environment, and an overactive immune system play a role. [1] UC is associated with comorbidities that produce symptoms in many areas of the body outside the digestive system.
The signs and symptoms of colitis are quite variable and dependent on the cause of the given colitis and factors that modify its course and severity. [2]Common symptoms of colitis may include: mild to severe abdominal pains and tenderness (depending on the stage of the disease), persistent hemorrhagic diarrhea with pus either present or absent in the stools, fecal incontinence, flatulence ...
Smoking is a major modifiable risk factor for Crohn's disease, particularly in Western countries, where it doubles the risk. This risk is higher in females and varies with age. Smoking is also linked to earlier disease onset, increased need for immunosuppression, more surgeries, and higher recurrence rates.
Closely trailing cancer as the most deadly smoking-related cause of death is ischemic heart disease, which was responsible for 126,000, or 28%, of all deaths.
In these cases, a diagnosis of indeterminate colitis may be made. [ 66 ] Irritable bowel syndrome can present with similar symptoms as either disease, as can nonsteroidal anti-inflammatory drug (NSAID) enteritis and intestinal tuberculosis .
Pancolitis or universal colitis, in its most general sense, refers to inflammation of the entire large intestine comprising the cecum, ascending, transverse, descending, sigmoid colon and rectum. It can be caused by a variety of things such as inflammatory bowel disease , more specifically a severe form of ulcerative colitis .
This is an accepted version of this page This is the latest accepted revision, reviewed on 10 December 2024. Circumstances, mechanisms, and factors of tobacco consumption on human health "Health effects of smoking" and "Dangers of smoking" redirect here. For cannabis, see Effects of cannabis. For smoking crack cocaine, see Crack cocaine § Health issues. "Smoking and health" redirects here ...
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