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Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [ 1 ]
In the new NHS trial, three patients have received the therapy for the most serious form of lupus, a condition that can be life-threatening and cause damage to the heart, lungs, brain and kidneys.
Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints , skin , kidneys , blood cells , heart , and lungs .
Lungs None specific Possible 20 per 100,000 (men), 13 per 100,000 (women) [84] Interstitial lung disease: Lungs Depends on the subtype (e.g. Anti-Jo1 in Anti-synthetase syndrome) Probable 31.5 per 100,000 (men), 26.1 per 100,000 (women) [85] Pulmonary alveolar proteinosis: Lungs Anti-GM-CSF antibodies Confirmed 6.2 per million [86] Rheumatoid ...
Common symptoms include extreme fatigue, joint pain or skin rashes. In rare cases, the disease may lead to kidney or heart damage, or weaken the immune system so the body can’t fight off infections.
According to the Mayo Clinic, lupus is a chronic autoimmune disease that "attacks your own tissues and organs" and can cause inflammation in a person's "joints, skin, kidneys, blood cells, brain ...
Lung procedures, like surgery, drainage of fluid with a needle, examination of the lung from the inside with a light and a camera, or mechanical ventilation, also can cause a pneumothorax. The most common symptom is sudden pain in one side of the lung and shortness of breath. A pneumothorax also can put pressure on the lung and cause it to ...
The oral drug, brepocitinib, did not meet the primary study goal of reduction in disease activity at week 52 in patients of SLE, in which the immune system that normally helps protect the body ...