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Fibrils (from Latin fibra [1]) are structural biological materials found in nearly all living organisms. Not to be confused with fibers or filaments , fibrils tend to have diameters ranging from 10 to 100 nanometers (whereas fibers are micro to milli-scale structures and filaments have diameters approximately 10–50 nanometers in size).
To date, 37 human proteins have been found to form amyloid in pathology and be associated with well-defined diseases. [2] The International Society of Amyloidosis classifies amyloid fibrils and their associated diseases based upon associated proteins (for example ATTR is the group of diseases and associated fibrils formed by TTR). [3]
Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. [4] There are several non-specific and vague signs and symptoms associated with amyloidosis. [5] These include fatigue, peripheral edema, weight loss, shortness of breath, palpitations, and feeling faint with standing. [5]
Fibrillogenesis is the development of fine fibrils normally present in collagen fibers of connective tissue. It is derived from the New Latin fibrilla (meaning fibrils, or pertaining to fibrils) and Greek genesis (to create, the process by which something is created).
As cellulose fibrils are synthesized and grow extracellularly they push up against neighboring cells. Since the neighboring cell can not move easily the Rosette complex is instead pushed around the cell through the fluid phospholipid membrane. Eventually this results in the cell becoming wrapped in a microfibril layer.
A myofibril (also known as a muscle fibril or sarcostyle) [1] is a basic rod-like organelle of a muscle cell. [2] Skeletal muscles are composed of long, tubular cells known as muscle fibers, and these cells contain many chains of myofibrils. [3]
Crazing is a yielding mechanism in polymers characterized by the formation of a fine network of microvoids and fibrils. [ 1 ] [ 2 ] These structures (known as crazes ) typically appear as linear features and frequently precede brittle fracture .
Asbestos (/ æ s ˈ b ɛ s t ə s, æ z-,-t ɒ s / ass-BES-təs, az-, -toss) [1] is a group of naturally occurring, toxic, carcinogenic and fibrous silicate minerals.There are six types, all of which are composed of long and thin fibrous crystals, each fibre (particulate with length substantially greater than width) [2] being composed of many microscopic "fibrils" that can be released into ...