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  2. XY sex-determination system - Wikipedia

    en.wikipedia.org/wiki/XY_sex-determination_system

    The idea is instead of having a simplistic mechanism by which you have pro-male genes going all the way to make a male, in fact there is a solid balance between pro-male genes and anti-male genes and if there is a little too much of anti-male genes, there may be a female born and if there is a little too much of pro-male genes then there will ...

  3. Hardy–Weinberg principle - Wikipedia

    en.wikipedia.org/wiki/Hardy–Weinberg_principle

    In the simplest case of a single locus with two alleles denoted A and a with frequencies f(A) = p and f(a) = q, respectively, the expected genotype frequencies under random mating are f(AA) = p 2 for the AA homozygotes, f(aa) = q 2 for the aa homozygotes, and f(Aa) = 2pq for the heterozygotes.

  4. Haldane's rule - Wikipedia

    en.wikipedia.org/wiki/Haldane's_rule

    In humans, barring intersex conditions causing aneuploidy and other unusual states, it is the male that is heterogametic, with XY sex chromosomes.. Haldane's rule is an observation about the early stage of speciation, formulated in 1922 by the British evolutionary biologist J. B. S. Haldane, that states that if — in a species hybrid — only one sex is inviable or sterile, that sex is more ...

  5. Sex-determination system - Wikipedia

    en.wikipedia.org/wiki/Sex-determination_system

    However, reportedly, the silkworm Bombyx mori uses a single female-specific piRNA as the primary determiner of sex. [25] Despite the similarities between the ZW and XY systems, these sex chromosomes evolved separately. In the case of the chicken, their Z chromosome is more similar to humans' autosome 9. [26]

  6. Sexual differentiation in humans - Wikipedia

    en.wikipedia.org/wiki/Sexual_differentiation_in...

    Figure One: The mesonephric System Pathway [7] Differentiation between the sexes of the sex organs occurs throughout embryological, fetal and later life. In both males and females, the sex organs consist of two structures: the internal genitalia and the external genitalia. In males, the gonads are the testicles and in females, they are the ovaries.

  7. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular gene in an ...

  8. Heterozygote advantage - Wikipedia

    en.wikipedia.org/wiki/Heterozygote_advantage

    The specific case of heterozygote advantage due to a single locus is known as overdominance. [2] [3] Overdominance is a rare [4] condition in genetics where the phenotype of the heterozygote lies outside of the phenotypical range of both homozygote parents, and heterozygous individuals have a higher fitness than homozygous individuals.

  9. Obligate carrier - Wikipedia

    en.wikipedia.org/wiki/Obligate_carrier

    In X-linked recessive disorders, only females can be the carriers of the recessive mutation, making them obligate carriers of this type of disease. Females acquire one X-chromosome from their father and one from their mother, and this means they can either be heterozygous for the mutated allele or homozygous. If heterozygous, she is a carrier ...

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