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This list of manually curated human transcription factors is taken from Lambert, Jolma, Campitelli et al. [1] It was assembled by manual curation. More detailed information is found in the manuscript and the web site accompanying the paper ( Human Transcription Factors )
•List of human protein-coding genes page 2 covers genes EPHA1–MTMR3 •List of human protein-coding genes page 3 covers genes MTMR4–SLC17A7 •List of human protein-coding genes page 4 covers genes SLC17A8–ZZZ3 NB: Each list page contains 5000 human protein-coding genes, sorted alphanumerically by the HGNC-approved gene symbol.
Other transcription factors differentially regulate the expression of various genes by binding to enhancer regions of DNA adjacent to regulated genes. These transcription factors are critical to making sure that genes are expressed in the right cell at the right time and in the right amount, depending on the changing requirements of the organism.
a comprehensive collection of human and mouse transcription factor binding sites models. database: website [10] JASPAR: The JASPAR CORE database contains a curated, non-redundant set of profiles, derived from published collections of experimentally defined transcription factor binding sites for eukaryotes. database: website [11] [12] MethMotif
A transcription factor is a protein that binds to specific DNA sequences (enhancer or promoter), either alone or with other proteins in a complex, to control the rate of transcription of genetic information from DNA to messenger RNA by promoting (serving as an activator) or blocking (serving as a repressor) the recruitment of RNA polymerase.
Pages in category "Transcription factors" The following 200 pages are in this category, out of approximately 733 total. This list may not reflect recent changes .
Interactions between bZIP transcription factors are numerous and complex [5] [6] [3] and play important roles in cancer development [7] in epithelial tissues, steroid hormone synthesis by cells of endocrine tissues, [8] factors affecting reproductive functions, [9] and several other phenomena that affect human health.
21676 Ensembl ENSG00000187079 ENSMUSG00000055320 UniProt P28347 P30051 RefSeq (mRNA) NM_021961 NM_001166584 NM_001166585 NM_009346 NM_175559 RefSeq (protein) NP_068780 NP_001160056 NP_001160057 NP_033372 Location (UCSC) Chr 11: 12.67 – 12.94 Mb Chr 7: 112.28 – 112.51 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcriptional enhancer factor TEF-1 also known as TEA domain ...