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Even if dimercaptosuccinic acid cannot reverse the damages done to the central nervous system, it might prevent further deterioration. [13] Succimer facilitates urinary excretion of lead, and with sufficiently aggressive treatment, can reduce lead content in the brain. [14] It also increases urinary excretion of copper and zinc. [15]
Cases of mass lead poisoning can occur. In 2009, 15,000 people were planned to be relocated from Jiyuan in central Henan province to other locations after 1000 children living around China's largest smelter plant (owned and operated by Yuguang Gold and Lead) were found to have excess lead in their blood. The total cost of this project is ...
Sodium calcium edetate's primary use is to treat lead poisoning, [2] for which it is an alternative to succimer. [3] It is given by slow injection into a vein or into a muscle. [2] For lead encephalopathy sodium calcium edetate is typically used together with dimercaprol. [3] It may also be used to treat plutonium poisoning. [5]
2. Baby Food. One might think that a product advertised for infants and young children would be safe to eat. Alas, it's shocking how much food marketed to kids contains lead.
An antidote is a substance that can counteract a form of poisoning. [1] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton) , "(medicine) given as a remedy".
Lead and cadmium: lead poisoning and cadmium poisoning can lead to gastrointestinal, kidney, and neurological dysfunction. The use of unleaded paints and gas has successfully decreased the number of cases of lead heavy metal poisoning. Nickel, chromium, and cadmium: via metal-DNA interactions, these metals can be carcinogenic. [3]
The Lead Exposure Elimination Project (LEEP) is an international non-governmental organization aimed at reducing lead exposure in low and middle income countries. [1] Based in London, England , it was founded in 2020 to promote research and advocacy on the prevalence and consequences of lead poisoning in the developing world. [ 1 ]
Dimercaprol has long been the mainstay of chelation therapy for lead or arsenic poisoning, [7] and it is an essential drug. [6] It is also used as an antidote to the chemical weapon Lewisite . Nonetheless, because it can have serious adverse effects , researchers have also pursued development of less toxic analogues, [ 7 ] such as succimer .