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For instance, a 71-year-old married non-smoking high school graduate with a performance status (PS) of 0, and no weight loss or anaemia and a T3N1 HPV+OPC would expect to have a progression-free survival of 92% at 2 years and 88% at 5 years. A 60-year-old unmarried nonsmoking high school graduate with a PS of 1, weight loss and anaemia, and a ...
Oropharyngeal cancer, [1] [2] [3] also known as oropharyngeal squamous cell carcinoma and tonsil cancer, [1] is a disease in which abnormal cells with the potential to both grow locally and spread to other parts of the body are found in the oral cavity, in the tissue of the part of the throat that includes the base of the tongue, the tonsils, the soft palate, and the walls of the pharynx.
HPV-positive oropharyngeal cancer generally has a better outcome than HPV-negative disease, with a 54% better survival rate, [18] but this advantage for HPV-associated cancer applies only to oropharyngeal cancers. [19] People with oropharyngeal carcinomas are at high risk of developing a second primary head and neck cancer. [20]
Esophageal cancer (lower part) as a result of Barrettʼs esophagus. Male predominance is particularly strong in this type of esophageal cancer, which occurs about 7 to 10 times more frequently in men. [25] This imbalance may be related to the characteristics and interactions of other known risk factors, including acid reflux and obesity. [25]
The stages of oropharyngeal cancer are as follows: [23] • Stage 0 (carcinoma in situ): This stage indicates a good prognosis as most patients with stage 0 survive for a long period without the requirement of an intensive treatment. Although, the patient must cease smoking as it can increase the risk of developing a new cancer.
The most common type (indicated in about 90%) of oral and oropharyngeal cancer is squamous cell carcinoma. [5] Approximately 63% of oropharyngeal squamous cell carcinomas each year are associated with HPV infection. [1] Most cases of HPV go undetected and clear up on their own without the patient ever knowing they had contracted it. [1] [2 ...
Smoking cigarettes had the largest impact on cancer rates, accounting for nearly 20% of cancers in 2019, meaning that as many as 206,550 cases and 103,000 deaths could have been prevented if all ...
In 2022, close to 54,000 Americans are projected to be diagnosed with oral or oropharyngeal cancer. 66% of the time, these will be found as late stage three and four disease. It will cause over 8,000 deaths. Of those newly diagnosed, only slightly more than half will be alive in five years. Similar survival estimates are reported from other ...
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