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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Spironolactone can cause hyperkalemia, or high blood potassium levels. [111] Rarely, this can be fatal. [111] Of people with heart disease prescribed typical dosages of spironolactone, 10 to 15% develop some degree of hyperkalemia, and 6% develop severe hyperkalemia. [111] At a higher dosage, a rate of hyperkalemia of 24% has been observed. [119]

  3. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    [24] [26] It has been determined that 7α-TMS accounts for around 80% of the potassium-sparing effect of spironolactone [1] [2] [3] while canrenone accounts for the remaining approximately 10 to 25%. [4] Accordingly, 7α-TMS occurs at higher circulating concentrations than does canrenone in addition to having a higher relative affinity for the ...

  4. Hyperkalemia - Wikipedia

    en.wikipedia.org/wiki/Hyperkalemia

    [1] [2] Hyperkalemia can cause an abnormal heart rhythm which can result in cardiac arrest and death. [1] [3] Common causes of hyperkalemia include kidney failure, hypoaldosteronism, and rhabdomyolysis. [1] A number of medications can also cause high blood potassium including spironolactone, NSAIDs, and angiotensin converting enzyme inhibitors. [1]

  5. Could Spironolactone Help Women With Hair Thinning, Facial ...

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  6. Potassium-sparing diuretic - Wikipedia

    en.wikipedia.org/wiki/Potassium-sparing_diuretic

    Potassium-sparing diuretics or antikaliuretics [1] refer to drugs that cause diuresis without causing potassium loss in the urine. [2] They are typically used as an adjunct in management of hypertension, cirrhosis, and congestive heart failure. [3] The steroidal aldosterone antagonists can also be used for treatment of primary hyperaldosteronism.

  7. Hyperaldosteronism - Wikipedia

    en.wikipedia.org/wiki/Hyperaldosteronism

    Treatment includes removing the causative agent (such as licorice), a high-potassium, low-sodium diet (for primary) and high-sodium diet (for secondary), spironolactone and eplerenone, potassium-sparing diuretics that act as aldosterone antagonists, and surgery, depending on the cause. [11] For adrenal adenoma, sometimes surgery is performed.

  8. Everything I Wish I Knew About Taking Spironolactone for Acne

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  9. The jobs most vulnerable under the next Trump administration

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    President-elect Donald Trump campaigned on the promise to create more American jobs and protect existing ones. But many of his proposals and expected policy changes threaten to have the opposite ...

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