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Therapy with a 5α-reductase inhibitor markedly reduces the DHT content of the prostate and, in turn, reduces prostate volume and BPH symptoms. [24] [25] Testosterone promotes prostate cell proliferation, [26] but relatively low levels of serum testosterone are found in patients with BPH.
Screening for prostate cancer may include a digital rectal exam, where the clinician assesses for an enlarged prostate, and/or a blood test to measure a prostate-specific antigen (PSA) level.
Testosterone therapy for patients with late-onset hypogonadism, in addition to increasing risk of cardiovascular disease and prostate cancer, may exacerbate the risk factors associated with benign prostatic hyperplasia, a condition that involves the noncancerous enlargement of the prostate gland, which can lead to urinary symptoms. [100]
“There are various management options available for managing symptoms of [an enlarged prostate], ranging from lifestyle modifications to medication, minimally invasive procedures and surgery ...
Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy in which androgens, often testosterone, are supplemented or replaced. It typically involves the administration of testosterone through injections, skin creams, patches, gels, pills, or subcutaneous pellets.
The symptoms of an enlarged prostate can include frequent urination and needing to get up many times in the night to pee. A man might have trouble getting started in the bathroom or dribbling when ...
As a result, free testosterone is diverted from the testicles into the prostate, thereby causing prostatic congestion. [4] Chronic prostatitis (infection of the prostate) – An infection of the prostate can lead to the buildup of fluid due to the bodies natural defense mechanism leading to inflammation. Along with excessive fluid production ...
This is because when the prostate is enlarged, it puts pressure on the bladder and the urethra. According to Prostate Cancer UK, urinary symptoms can include: – A weak flow when you urinate
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