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OPCs continue to exist in both white and grey matter in the adult brain and maintain their population through self-renewal. [29] [30] White matter OPCs proliferate at higher rates and are best known for their contributions to adult myelinogenesis, while grey matter OPCs are slowly proliferative or quiescent and mostly remain in an immature state.
They are the most widespread cell lineage, including oligodendrocyte progenitor cells, pre-myelinating cells, and mature myelinating oligodendrocytes in the CNS white matter. [3] Non-myelinating oligodendrocytes are found in the grey matter surrounding and lying next to neuronal cell bodies. They are known as neuronal satellite cells, and their ...
White matter is the tissue through which messages pass between different areas of grey matter within the central nervous system. The white matter is white because of the fatty substance (myelin) that surrounds the nerve fibers (axons). This myelin is found in almost all long nerve fibers, and acts as an electrical insulation.
Grey matter, or gray matter in American English, is a major component of the central nervous system, consisting of neuronal cell bodies, neuropil (dendrites and unmyelinated axons), glial cells (astrocytes and oligodendrocytes), synapses, and capillaries.
[5] [1] This zone is only present during corticogenesis and eventually transforms into adult white matter. The ventricular and subventricular zones exist inferior to the intermediate zone and communicate with other zones through cell signalling. These zones additionally create neurons destined to migrate to other areas in the cortex. [1] [6]
Projections of the gray matter (the “wings”) are called horns. Together, the gray horns and the gray commissure form the “gray H.” The white matter is located outside of the gray matter and consists almost totally of myelinated motor and sensory axons. “Columns” of white matter carry information either up or down the spinal cord.
The vertebrate nervous system can also be divided into areas called gray matter and white matter. [19] Gray matter (which is only gray in preserved tissue, and is better described as pink or light brown in living tissue) contains a high proportion of cell bodies of neurons. White matter is composed mainly of myelinated axons, and takes its ...
Tangential growth suggests that the grey matter grows at a faster rate than the inner white matter and that the growth rate of the grey matter determines the growth rate of the white matter. Though both methods are differential, with the cortex growing more rapidly than the subcortex, tangential growth has been suggested as a more plausible model.