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Equine estrogens, or horse estrogens, are estrogens found in horses. [1] [2] [3] They include the following: [1] [2] [3] Estradiol; Estrone; Equilin (Δ 7-estrone) Equilenin (Δ 6,8-estrone) 17α-Dihydroequilin (Δ 7-17α-estradiol) 17β-Dihydroequilin (Δ 7-17β-estradiol) 17α-Dihydroequilenin (Δ 6,8-17α-estradiol) 17β-Dihydroequilenin (Δ ...
[1] [7] The equine estrogens differ from human estrogens in that they have additional double bonds in the B ring of the steroid nucleus. [1] [7] CEEs contain both 17β-estrogens like estradiol and 17β-dihydroequilin and the C17α epimers like 17α-estradiol and 17α-dihydroequilin. [1] [7
Conjugated estrogens/medroxyprogesterone acetate (CEs/MPA), sold under the brand names Prempro and Premphase, is a combination product of conjugated equine estrogens (Premarin), an estrogen collected from horse urine, and medroxyprogesterone acetate (Provera), a progestogen, which is used in menopausal hormone therapy for the treatment of menopausal symptoms.
Equilin is a naturally occurring estrogen sex hormone found in horses as well as a medication. [1] [2] [3] It is one of the estrogens present in the estrogen combination drug preparations known as conjugated estrogens (CEEs; e.g. Premarin) and esterified estrogens (EEs; e.g. Estratab, Menest).
Of these participants, 15,350 were on an HRT of either estrogen or estrogen plus progestogen, and 13,937 received a placebo. The participants’ mean ages ranged from 47 to 75, and their treatment ...
8,9-Dehydroestradiol, or Δ 8-17β-estradiol, also known as estra-1,3,5(10),8-tetraen-17β-ol-3-one, is a naturally occurring steroidal estrogen found in horses which is closely related to equilin, equilenin, and estradiol, and, as the 3-sulfate ester sodium salt, is a minor constituent of conjugated estrogens (Premarin). [1]
17β-Dihydroequilin is a naturally occurring estrogen sex hormone found in horses as well as a medication. [1] [2] As the C3 sulfate ester sodium salt, it is a minor constituent (1.7%) of conjugated estrogens (CEEs; brand name Premarin). [1]
Estradiol (E2) is a medication and naturally occurring steroid hormone. [11] [12] [13] It is an estrogen and is used mainly in menopausal hormone therapy and to treat low sex hormone levels in women.
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